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Inhibition of mTOR Signaling in Parkinson’s Disease Prevents l-DOPA–Induced Dyskinesia

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Science Signaling  21 Jul 2009:
Vol. 2, Issue 80, pp. ra36
DOI: 10.1126/scisignal.2000308

Article Information

vol. 2 no. 80 ra36

DOI: 
https://doi.org/10.1126/scisignal.2000308
PubMed: 
19622833
Published By: 
Science Signaling
Print ISSN: 
1945-0877
Online ISSN: 
1937-9145
History: 
  • Received March 6, 2009
  • Accepted July 1, 2009
  • .
Copyright & Usage: 
Copyright © 2009, American Association for the Advancement of Science

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  • Inhibition of mTOR Signaling in Parkinson’s Disease Prevents l-DOPA–Induced Dyskinesia

    By Emanuela Santini, Myriam Heiman, Paul Greengard, Emmanuel Valjent, Gilberto Fisone

    Science Signaling : ra36

    Dyskinetic side effects of a Parkinson’s disease medication may involve dopamine D1 receptor–mediated activation of mTORC1.

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