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vol. 2 no. 81 ra39
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- Received March 10, 2009
- Accepted July 6, 2009
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Copyright © 2009, American Association for the Advancement of Science
Research ArticleCOMPUTATIONAL BIOLOGY
Comparative Analysis Reveals Conserved Protein Phosphorylation Networks Implicated in Multiple Diseases
- Chris Soon Heng Tan1,2,*,
- Bernd Bodenmiller3,*,
- Adrian Pasculescu1,
- Marko Jovanovic4,
- Michael O. Hengartner4,
- Claus Jørgensen1,
- Gary D. Bader1,2,
- Ruedi Aebersold3,5,6,7,
- Tony Pawson1,2, and
- Rune Linding8,†
- 1Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada M5G 1X5.
- 2Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada M5S 1A8.
- 3Institute of Molecular Systems Biology, Eidgenössische Technische Hochschule (ETH), 8093 Zurich, Switzerland.
- 4Institute of Molecular Biology, University of Zurich, 8057 Zurich, Switzerland.
- 5Institute for Systems Biology, Seattle, WA 98103, USA.
- 6Competence Center for Systems Physiology and Metabolic Diseases, ETH Zurich, 8093 Zurich, Switzerland.
- 7Faculty of Science, University of Zurich, 8057 Zurich, Switzerland.
- 8Cellular & Molecular Logic Team, Section of Cell and Molecular Biology, The Institute of Cancer Research (ICR), London SW3 6JB, UK.
- ↵†To whom correspondence should be addressed. E-mail: linding{at}icr.ac.uk
-
↵* These authors contributed equally to this work.
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Science Signaling 28 Jul 2009:
Vol. 2, Issue 81, pp. ra39
DOI: 10.1126/scisignal.2000316
Vol. 2, Issue 81, pp. ra39
DOI: 10.1126/scisignal.2000316
Chris Soon Heng Tan
1Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada M5G 1X5.
2Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada M5S 1A8.
Bernd Bodenmiller
3Institute of Molecular Systems Biology, Eidgenössische Technische Hochschule (ETH), 8093 Zurich, Switzerland.
Adrian Pasculescu
1Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada M5G 1X5.
Marko Jovanovic
4Institute of Molecular Biology, University of Zurich, 8057 Zurich, Switzerland.
Michael O. Hengartner
4Institute of Molecular Biology, University of Zurich, 8057 Zurich, Switzerland.
Claus Jørgensen
1Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada M5G 1X5.
Gary D. Bader
1Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada M5G 1X5.
2Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada M5S 1A8.
Ruedi Aebersold
3Institute of Molecular Systems Biology, Eidgenössische Technische Hochschule (ETH), 8093 Zurich, Switzerland.
5Institute for Systems Biology, Seattle, WA 98103, USA.
6Competence Center for Systems Physiology and Metabolic Diseases, ETH Zurich, 8093 Zurich, Switzerland.
7Faculty of Science, University of Zurich, 8057 Zurich, Switzerland.
Tony Pawson
1Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada M5G 1X5.
2Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada M5S 1A8.
Rune Linding
8Cellular & Molecular Logic Team, Section of Cell and Molecular Biology, The Institute of Cancer Research (ICR), London SW3 6JB, UK.
