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vol. 2 no. 82 ra41
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History:
- Received March 26, 2009
- Accepted July 10, 2009
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Copyright © 2009, American Association for the Advancement of Science
Research ArticleAngiogenesis
The Akt1-eNOS Axis Illustrates the Specificity of Kinase-Substrate Relationships in Vivo
- Michael Schleicher1,
- Jun Yu1,
- Takahisa Murata2,
- Berhad Derakhshan1,
- Dimitriy Atochin3,
- Li Qian3,
- Satoshi Kashiwagi3,
- Annarita Di Lorenzo1,
- Kenneth D. Harrison1,
- Paul L. Huang3,*, and
- William C. Sessa1,*
- 1Department of Pharmacology and Vascular Biology and Therapeutics Program, Amistad Building, Yale University School of Medicine, New Haven, CT 06520, USA.
- 2Department of Veterinary Pharmacology, Graduate School of Agriculture and Life Sciences, University of Tokyo, Bunkyo-ku, Tokyo 113-8657, Japan.
- 3Cardiovascular Research Center and Cardiology Division, Massachusetts General Hospital, Boston, MA 02129, USA.
- ↵*To whom correspondence should be addressed. E-mail: huangp{at}helix.mgh.harvard.edu (P.L.H.) and william.sessa{at}yale.edu (W.C.S.)
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Science Signaling 04 Aug 2009:
Vol. 2, Issue 82, pp. ra41
DOI: 10.1126/scisignal.2000343
Vol. 2, Issue 82, pp. ra41
DOI: 10.1126/scisignal.2000343
Michael Schleicher
1Department of Pharmacology and Vascular Biology and Therapeutics Program, Amistad Building, Yale University School of Medicine, New Haven, CT 06520, USA.
Jun Yu
1Department of Pharmacology and Vascular Biology and Therapeutics Program, Amistad Building, Yale University School of Medicine, New Haven, CT 06520, USA.
Takahisa Murata
2Department of Veterinary Pharmacology, Graduate School of Agriculture and Life Sciences, University of Tokyo, Bunkyo-ku, Tokyo 113-8657, Japan.
Berhad Derakhshan
1Department of Pharmacology and Vascular Biology and Therapeutics Program, Amistad Building, Yale University School of Medicine, New Haven, CT 06520, USA.
Dimitriy Atochin
3Cardiovascular Research Center and Cardiology Division, Massachusetts General Hospital, Boston, MA 02129, USA.
Li Qian
3Cardiovascular Research Center and Cardiology Division, Massachusetts General Hospital, Boston, MA 02129, USA.
Satoshi Kashiwagi
3Cardiovascular Research Center and Cardiology Division, Massachusetts General Hospital, Boston, MA 02129, USA.
Annarita Di Lorenzo
1Department of Pharmacology and Vascular Biology and Therapeutics Program, Amistad Building, Yale University School of Medicine, New Haven, CT 06520, USA.
Kenneth D. Harrison
1Department of Pharmacology and Vascular Biology and Therapeutics Program, Amistad Building, Yale University School of Medicine, New Haven, CT 06520, USA.
Paul L. Huang
3Cardiovascular Research Center and Cardiology Division, Massachusetts General Hospital, Boston, MA 02129, USA.
William C. Sessa
1Department of Pharmacology and Vascular Biology and Therapeutics Program, Amistad Building, Yale University School of Medicine, New Haven, CT 06520, USA.
