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Research ArticleMorphogenesis
Differential Interactions of FGFs with Heparan Sulfate Control Gradient Formation and Branching Morphogenesis
- Helen P. Makarenkova1,2,*,†,
- Matthew P. Hoffman3,*,
- Andrew Beenken4,
- Anna V. Eliseenkova4,
- Robyn Meech2,5,
- Cindy Tsau1,
- Vaishali N. Patel3,
- Richard A. Lang6, and
- Moosa Mohammadi4,*
- 1The Neurobiology Department, The Scripps Research Institute, La Jolla, CA 92037, USA.
- 2The Neurosciences Institute, San Diego, CA 92121, USA.
- 3Laboratory of Cell and Developmental Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892, USA.
- 4Department of Pharmacology, New York University School of Medicine, New York, NY 10016, USA.
- 5Department of Clinical Pharmacology, Flinders University, Bedford Park, South Australia 5042, Australia.
- 6The Visual Systems Group, Department of Ophthalmology and Division of Developmental Biology, Children’s Hospital Research Foundation, Cincinnati, OH 45229, USA.
- ↵†To whom correspondence should be addressed. E-mail: hmakarenk{at}scripps.edu
-
↵* These authors contributed equally to this work.
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Science Signaling 15 Sep 2009:
Vol. 2, Issue 88, pp. ra55
DOI: 10.1126/scisignal.2000304
Vol. 2, Issue 88, pp. ra55
DOI: 10.1126/scisignal.2000304
Helen P. Makarenkova
1The Neurobiology Department, The Scripps Research Institute, La Jolla, CA 92037, USA.
2The Neurosciences Institute, San Diego, CA 92121, USA.
Matthew P. Hoffman
3Laboratory of Cell and Developmental Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892, USA.
Andrew Beenken
4Department of Pharmacology, New York University School of Medicine, New York, NY 10016, USA.
Anna V. Eliseenkova
4Department of Pharmacology, New York University School of Medicine, New York, NY 10016, USA.
Robyn Meech
2The Neurosciences Institute, San Diego, CA 92121, USA.
5Department of Clinical Pharmacology, Flinders University, Bedford Park, South Australia 5042, Australia.
Cindy Tsau
1The Neurobiology Department, The Scripps Research Institute, La Jolla, CA 92037, USA.
Vaishali N. Patel
3Laboratory of Cell and Developmental Biology, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD 20892, USA.
Richard A. Lang
6The Visual Systems Group, Department of Ophthalmology and Division of Developmental Biology, Children’s Hospital Research Foundation, Cincinnati, OH 45229, USA.
Moosa Mohammadi
4Department of Pharmacology, New York University School of Medicine, New York, NY 10016, USA.
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