Editors' ChoiceReview

ErbB Signaling

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Science's STKE  11 Jul 2000:
Vol. 2000, Issue 40, pp. tw12
DOI: 10.1126/stke.2000.40.tw12

Olayioye et al. have written a review on the ErbB receptors and their ligands. The review covers how receptor homo- and heterodimerization contribute to signaling complexity and specificity. Special emphasis is placed on the role of ErbB pathways in development and in cancer.

Olayioye, M.A., Neve, R.M., Lane, H.A., and Hynes, N.E. (2000) The ErbB signaling network: receptor heterodimerization in development and cancer. EMBO J. 19: 3159-3167. [Full Text]

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