Editors' ChoiceReview

Feedback Loops

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Science's STKE  21 Nov 2000:
Vol. 2000, Issue 59, pp. tw10
DOI: 10.1126/stke.2000.59.tw10

Feedback loops are important mechanisms by which cells and organisms can regulate signal strength, duration, and location. Freeman describes how positive and negative feedback loops control a variety of developmental processes. The review deals specifically with examples for which there is experimental evidence as opposed to the theoretical modeling literature.

Freeman, M. (2000) Feedback control of intercellular signalling in development. Nature 408: 313-319. [Online Journal]

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