Editors' ChoiceCircadian Rhythms

Piecing Together the Clock in Plants

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Science's STKE  07 Aug 2001:
Vol. 2001, Issue 94, pp. tw7
DOI: 10.1126/stke.2001.94.tw7

The circadian clocks translate cyclic changes in molecular function into daily cycles that anticipate and coordinate with environmental cues. Alabadí et al. now delve into the molecular rhythms of the plant circadian clock and define the molecular partners. A pair of transcriptions factors, LHY and CCA1, begin the morning and, throughout the day, gradually turn over the reins to the evening gene, TOC1. The reciprocating balance between these various genes establishes the basis of the circadian cycle in Arabidopsis.

D. Alabadí, T. Oyama, M. J. Yanovsky, F. G. Harmon, P. Más, S. A. Kay, Reciprocal regulation between TOC1 and LHY/CCA1 within the Arabidopsis circadian clock. Science 293, 880-883 (2001). [Abstract] [Full Text]

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