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Contents

28 March 2006
Vol 2006, Issue 328

Contents
- Perspectives
  - BRAF and MEK Mutations Make a Late Entrance
    
    By Nick Duesbery, George Vande Woude
    
    Science's STKE28 Mar 2006 : pe15 Full AccessRestricted Access
    
    Abstract
    
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  - Multiple Thermometers in Mammalian Cells: Why Do Cells from Homeothermic Organisms Need to Measure Temperature?
    
    By Michael Y. Sherman, Vladimir L. Gabai
    
    Science's STKE28 Mar 2006 : pe16 Full AccessRestricted Access
    
    Abstract
    
    Full Text
    
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- Editors' Choice
  - Linking HSF1 Activation to Translation
    
    Science's STKE28 Mar 2006 : tw105 Full AccessRestricted Access
    
    Abstract
  - The Many Partners of PUMILIO
    
    Science's STKE28 Mar 2006 : tw106 Full AccessRestricted Access
    
    Abstract
  - Vacillating About a Fateful Decision
    
    Science's STKE28 Mar 2006 : tw107 Full AccessRestricted Access
    
    Abstract
  - Holding onto Two Jobs
    
    Science's STKE28 Mar 2006 : tw109 Full AccessRestricted Access
    
    Abstract
  - Shedding Light on Tuberculosis Susceptibility
    
    Science's STKE28 Mar 2006 : tw110 Full AccessRestricted Access
    
    Abstract
  - A Foe Motif
    
    Science's STKE28 Mar 2006 : tw111 Full AccessRestricted Access
    
    Abstract
- - Excitable Model of Bacterial Competence
    
    Science's STKE28 Mar 2006 : tw108 Full AccessRestricted Access
    
    Abstract

About The Cover

Cover image expansion

COVER This week features a Perspective on germline mutations in KRAS, BRAF, and MEK1 and 2 that can lead to specific developmental syndromes. The image shows the pattern of phosphorylated ERK expression in a mouse embryo. [Image: J. Rossant, Toronto Sick Kids Hospital]