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Abstract
This week’s issues of Science and Science’s STKE are devoted to cancer research and to exploring how recent discoveries may impact our ability to diagnose and treat cancer. Science's STKE focuses on mechanisms by which growth factor–mediated stimulation of hypoxia-inducible factor signaling contributes to cancer progression and research that suggests a role as a tumor suppressor for a splicing variant of the c-H-ras oncogene.
