Contents
Vol 2007, Issue 369
Contents
Perspective
- Proline-Rich Regions in Transcriptional Complexes: Heading in Many Directions
Proteins swap domains to preserve overall organization of a transcriptional complex.
Editors' Choice
- Sensing Nuclear Glucose
Glucose acts as a ligand for LXR, a nuclear receptor activated by oxysterols.
- How Flies Find Fungal Foes
Fruit flies can detect fungal infections by sensing either the fungal cell wall or virulence factors.
- Mounting a Response to Viral Infection
Repressor domains acting in cis or trans govern the activity of the viral RNA sensor RIG-1.
- Separate Ways
A transcription factor controls the development of immune cells, supporting growth of one of the two major subsets of T cells while opposing differentiation of the other.
- Describing Delicate Interactions
A microfluidic method for measuring low-affinity molecular interactions characterizes transcription factor binding to DNA.
- One Ubiquitin, Two Ubiquitin, Three Ubiquitin, Four
This review describes the functions of ubiquitin beyond mediation of protein degradation.
Erratum
- Interference in the Secondary
In RNA-directed gene silencing in worms, an unanticipated class of small antisense RNAs is synthesized by cellular RNA-directed RNA polymerase.