06 February 2007
Vol 2007, Issue 372
  • Contents

    • Perspective

    • Editors' Choice

      • Diversifying Role for β-Arrestin

        A regulatory protein that limits the extent of signaling through a well-described class of receptor performs the same function for another receptor class, but by a completely different mechanism.

      • Mitochondrial Diversion and Aging

        A protein that prolongs life span when mutated has oxidoreductase activity in mitochondria where it generates toxic oxygen radicals, suggesting a possible therapeutic target.

      • Maintaining a Barrier

        Dual oxidase 1 plays a key role in repair of airway epithelium.

About The Cover

Cover image expansion

COVER This week features a Perspective on the role of kinesin superfamily proteins in neuronal polarization. The image depicts the local synthesis and kinesin-mediated delivery of PIP3. [Image: Christopher Bickel, AAAS]