Contents
Vol 2007, Issue 375
Contents
Editors' Choice
- Customizing MicroRNAs
Editing of a particular miRNA--changing adenosine to inosine--alters which mRNAs the miRNA targets for degradation, which in turn changes uric acid levels in the brain.
- G Protein-Mediated Inhibition of Autophagy
A Gi protein is implicated in regulation of autophagy in the liver.
- Death Effector Domain as a Transcriptional Regulator
The cleaved DED of caspase 8 serves as a positive feedback signal by stimulating production of procaspase 8.
- Dueling Regulators
Phosphoinositide regulation of calmodulin binding may represent a common mechanism for modulating ion channel function.
- Sugar-Coating the Road to Atherosclerosis
The hexosamine pathway and the glycosylation of nuclear proteins may be a link between hyperglycemia and the development of atherosclerosis.
- Smelling Their Way to an Early Grave
In flies, the ability of a severely calorie-restricted diet to extend life span can be partially reversed by exposing the flies to the odor of their main food, yeast.
- Coordinating Plant Defenses
Plant immune receptors that detect pathogen attack triggered resistance responses by de-repressing a transcriptional regulatory loop.
Erratum
