03 April 2007
Vol 2007, Issue 380
  • Contents

    • Perspective

    • Teaching Resource

    • Editors' Choice

      • Those Anxious Adolescents

        Reversal of the effects of neurosteroids in the hippocampus at puberty may underlie the highly emotional responses of teens.

      • Pollution Disrupts Endocrine Signaling

        The aryl hydrocarbon receptor that binds the environmental pollutant dioxin forms an E3 ubiquitin ligase complex that promotes the degradation of steroid receptors.

      • A Volatile Response to Injury

        Volatile organic compounds appear to act as an intraplant defense signal.

      • Epithelia Control Gut Inflammation

        Without NF-κB signaling in the epithelial cells of the intestine, animals are prone to infection and intestinal inflammation.

      • ASKing Macrophages to Promote Hair Growth

        The recruitment and activation of macrophages appears to play a critical role in promoting post-injury hair growth.

      • Key to Liver Regeneration

        A receptor for a factor that supports survival of neuronal cells is unexpectedly also required for liver regeneration after damage.

      • Two Ways to Segment an Insect

        Even though the head-tail axes of wasps and fruit flies develop similarly, they use two entirely different molecular mechanisms.

      • Targeting Transmembrane Domains

        Synthetic peptides can be designed to bind with high affinity and specificity to the regions of membrane proteins that span the lipid bilayer of the cell.

About The Cover

Cover image expansion

COVER This week features a Teaching Resource on molecular events involved in the activation of apoptosis by the death receptor Fas. The image depicts activation of caspase 8 at the activated death receptor and adaptor protein complex. [Image: Drew Berry, The Walter and Eliza Hall Institute of Medical Research, Victoria, Australia]