You are currently viewing the abstract.
View Full TextLog in to view the full text
AAAS login provides access to Science for AAAS members, and access to other journals in the Science family to users who have purchased individual subscriptions.
Register for free to read this article
As a service to the community, this article is available for free. Existing users log in.
More options
Download and print this article for your personal scholarly, research, and educational use.
Buy a single issue of Science for just $15 USD.
Abstract
When exploring control of a biological system such as the inflammatory response, we often think first of mechanisms that promote activation of the system. But just as important are the signals that that modulate and terminate these processes. Unchecked recruitment and infiltration of leukocytes into tissues and the unrestrained production of pro-inflammatory cytokines and chemokines can lead to tissue damage and even cancer. This issue of Science’s STKE highlights studies that enhance our understanding of how pro-inflammatory signals are switched on, and--equally important--how they are switched off.