Contents
Vol 2007, Issue 400
Contents
Editorial Guide
- Focus Issue: Cells on the Move
New research challenges some established models for multiple aspects of directed cell movement.
Perspective
- Signals on the Move: Chemokine Receptors and Organogenesis in Zebrafish
A single signal elicits distinct responses in different populations of cells in the zebrafish lateral line primordium.
Review
- Filopodia: The Fingers That Do the Walking
New and old players are involved in the formation of filopodia.
Protocol
- Methods for Pseudopodia Purification and Proteomic Analysis
Cells cultured on microporous filters allow the analysis of cellular extensions separately from the bulk of the cell body.
Editors' Choice
- Chillin’ Channels Through Internalization
Opening of voltage-gated L-type calcium channels leads to their removal from the cell membrane.
- Osteocytes Losing Their Grip?
Glucocorticoids elicit osteocyte apoptosis by inhibiting cell adhesion.
- Notch Sees Clearly
Notch1 links vitamin A metabolism to the maintenance of a healthy cornea.
- XRab40 Participates in a Ubiquitin Ligase Complex
XRab40 participates in a Cullin-based ubiquitin ligase complex that regulates noncanonical Wnt signaling and plays a critical role in Xenopus gastrulation.
- Hold Them Back
14-3-3 proteins are required to inhibit the activity of brassinosteroid-dependent transcription factors.
- Fleeting Memories
Even long after consolidation of a stable memory in rats, the activity of a particular protein kinase isoform is required in the cortex for its persistence.
- Smell the CO2
Mice can sense near-atmospheric concentrations of CO2 using a subset of olfactory neurons that may use the catabolic enzyme carbonic anhydrase.
- Understanding Selective Synapse Elimination
In developing worms, the pruning of excess synapses requires proteasome-mediated protein degradation and is selectively prevented by a neural adhesion molecule.
