Contents
Vol 2007, Issue 401
Contents
Perspective
- The Functions of Plant TIR Domains
Plants have evolved novel uses for the TIR domain in pathogen detection and possibly in controlling transcription factors as well.
Review
- Structure and Function of the PB1 Domain, a Protein Interaction Module Conserved in Animals, Fungi, Amoebas, and Plants
Canonical and noncanonical PB1 interactions contribute to cell organization and function.
Editors' Choice
- Master Energy-Regulator Kinases in Plants
Diverse stimuli control plant metabolism through a pair of protein kinases related to the adenosine monophosphate-activated protein kinase of mammals.
- Helping p53 Choose a Target Gene
Two new players in the game controlling p53 target gene promoter choice are Hzf and CAS (cellular apoptosis susceptibility protein).
- Playing on Both Sides of the Field
The proapoptotic proteins Bax and Bak also mediate T cell proliferation.
- Toll-like Receptor 2 and Type 1 Diabetes
TLR2 links clearance of apoptotic β cells with autoimmunity in the pancreas.
- Optineurin Competes with NEMO
Optineurin and NEMO both bind to proteins with lysine 63-linked polyubiquitin chains, but have opposing effects on NF-κB signaling.
- Is Wnt a Synaptomorphogen?
In Caenorhabditis elegans, Wnt signaling appears to prevent ectopic synapse formation.
- A Silent Partner
The Tribolium castaneum Ultraspiracle is an inactive partner of the ecdysone receptor.
- Astrocytes at Single Synapses
Certain synapses strengthen upon coincident secretion of the neurotransmitter glutamate from a neighboring astrocyte, suggesting that astrocytes contribute to learning.
- Bacteria Seeing Blue
A light-activated enzyme with a flavin chromophore is found in several bacterial species, and in one of these it regulates light-stimulated macrophage infection.
- Let's Get Together
Clusters of about 75 molecules of the membrane protein syntaxin result from weak attraction among the proteins balanced by steric repulsion induced by crowding.
Erratum
