26 January 2010
Vol 3, Issue 106

About The Cover

Cover image expansion

Online Cover: This week features a Research Article that describes the crystal structure of the calcium/calmodulin (CaM)–dependent protein kinase (CaMK) death-associated protein kinase (DAPK) in association with CaM. When in a complex with DAPK protein, CaM adopted an extended conformation that was different from that adopted by CaM bound to a peptide consisting of the DAPK autoregulatory domain. The image is the structure of the DAPK-CaM complex. [Credit: Matthias Wilmanns, EMBL-Hamburg, Germany]