02 February 2010
Vol 3, Issue 107
  • Contents

    • Research Article

    • Meeting Report

      • BMPs: From Bone to Body Morphogenetic Proteins

        Discussion at a meeting in Berlin, Germany, showed that BMPs have essential functions in organs and tissues besides bone.

    • Podcast

    • Editors' Choice

      • Signaling Stop from the Inside

        A fragment specific to Nogo-A is internalized to trigger growth cone collapse.

      • Double Trouble

        Neighboring cells with distinct mutations can cooperate to form invasive tumors.

      • Cellular Plasticity

        T helper 2 (TH2) cells can be induced to adopt both TH1 and TH2 phenotypes in the context of viral infection.

      • Effecting Entry

        Anthrax toxin stimulates intracellular signaling events to facilitate its entry into the target cell.

      • Keeping the Host Live

        Parasitic worms secrete proteases that when internalized suppress the immune response to promote an anti-inflammatory environment.

      • Gut Check

        Ionizing radiation destroys gastrointestinal epithelial cells by a mechanism that appears to be independent of apoptosis.

      • Promoting Axon Formation

        Cyclic adenosine monophosphate and cyclic guanosine monophosphate regulate axon formation and exert opposite actions on dendrite formation.

      • Dueling Kinases Finesse the Fat

        The energy-sensing kinase AMPK is coupled to hormonal control of metabolism through PKA.

About The Cover

Cover image expansion

Online Cover This week's issue features a Meeting Report on a conference that was held in Berlin, Germany, from 6 to 9 September 2009, on the effects of bone morphogenetic proteins (BMPs) on structures and processes throughout the body. [Image: Yana Greenman, AAAS]