Research ArticleCell Biology Apoptotic Cells Activate the “Phoenix Rising” Pathway to Promote Wound Healing and Tissue Regeneration Fang Li1, Qian Huang1,2,3, Jiang Chen4,5, Yuanlin Peng6, Dennis R. Roop4,5, Joel S. Bedford6, and Chuan-Yuan Li1,5,7,*1Department of Radiation Oncology, University of Colorado School of Medicine, Aurora, CO 80045, USA.2Center for Laboratory Research, First People’s Hospital, Shanghai Jiaotong University, Shanghai 200080, China.3National Laboratory for Oncogene and Related Genes Research, Cancer Institute of Shanghai Jiaotong University, Shanghai 200032, China.4Department of Dermatology, University of Colorado School of Medicine, Aurora, CO 80045, USA.5Charles C. Gates Regenerative Medicine and Stem Cell Biology Program, University of Colorado School of Medicine, Aurora, CO 80045, USA.6Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO 80523, USA.7Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO 80045, USA.↵*To whom correspondence should be addressed. E-mail: Chuan.Li{at}ucdenver.edu See allHide authors and affiliations Science Signaling 23 Feb 2010:Vol. 3, Issue 110, pp. ra13DOI: 10.1126/scisignal.2000634 Fang Li 1Department of Radiation Oncology, University of Colorado School of Medicine, Aurora, CO 80045, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site Qian Huang 1Department of Radiation Oncology, University of Colorado School of Medicine, Aurora, CO 80045, USA.2Center for Laboratory Research, First People’s Hospital, Shanghai Jiaotong University, Shanghai 200080, China.3National Laboratory for Oncogene and Related Genes Research, Cancer Institute of Shanghai Jiaotong University, Shanghai 200032, China.Find this author on Google Scholar Find this author on PubMed Search for this author on this site Jiang Chen 4Department of Dermatology, University of Colorado School of Medicine, Aurora, CO 80045, USA.5Charles C. Gates Regenerative Medicine and Stem Cell Biology Program, University of Colorado School of Medicine, Aurora, CO 80045, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site Yuanlin Peng 6Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO 80523, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site Dennis R. Roop 4Department of Dermatology, University of Colorado School of Medicine, Aurora, CO 80045, USA.5Charles C. Gates Regenerative Medicine and Stem Cell Biology Program, University of Colorado School of Medicine, Aurora, CO 80045, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site Joel S. Bedford 6Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO 80523, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site Chuan-Yuan Li 1Department of Radiation Oncology, University of Colorado School of Medicine, Aurora, CO 80045, USA.5Charles C. Gates Regenerative Medicine and Stem Cell Biology Program, University of Colorado School of Medicine, Aurora, CO 80045, USA.7Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO 80045, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site For correspondence: Chuan.Li@ucdenver.edu Article Figures & Data Info & Metrics eLetters PDF Article Information vol. 3 no. 110 ra13 DOI: https://doi.org/10.1126/scisignal.2000634 PubMed: 20179271 Published By: Science Signaling Print ISSN: 1945-0877 Online ISSN: 1937-9145 History: Received September 9, 2009Accepted February 8, 2010 . 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Apoptotic Cells Activate the “Phoenix Rising” Pathway to Promote Wound Healing and Tissue Regeneration By Fang Li, Qian Huang, Jiang Chen, Yuanlin Peng, Dennis R. Roop, Joel S. Bedford, Chuan-Yuan Li Science Signaling23 Feb 2010 : ra13 Caspases in dying cells trigger the release of growth signals that promote tissue repair.
Apoptotic Cells Activate the “Phoenix Rising” Pathway to Promote Wound Healing and Tissue Regeneration By Fang Li, Qian Huang, Jiang Chen, Yuanlin Peng, Dennis R. Roop, Joel S. Bedford, Chuan-Yuan Li Science Signaling23 Feb 2010 : ra13 Caspases in dying cells trigger the release of growth signals that promote tissue repair.