02 March 2010
Vol 3, Issue 111

About The Cover

Cover image expansion

Online Cover This week's issue features a Research Article that describes the crystal structure of the α-kinase domain (A-CAT) of Dictyostelium myosin II heavy chain kinase A (MHCK A), a member of the atypical α-kinase family of serine and threonine protein kinases. Details from this structure reveal features that distinguish α-kinases from conventional protein kinases. The image shows the distribution of electrostatic potential on the surface of A-CAT. [Image: Graham P. Côté, Department of Biochemistry, Queen's University, Kingston, Ontario, Canada]