Research ArticleGPCR SIGNALING Regulation of G Protein–Coupled Receptor Signaling: Specific Dominant-Negative Effects of Melanocortin 2 Receptor Accessory Protein 2 Julien A. Sebag and Patricia M. Hinkle*Department of Pharmacology and Physiology, University of Rochester Medical Center, Rochester, NY 14642, USA.↵*To whom correspondence should be addressed. E-mail: Patricia_Hinkle{at}urmc.rochester.edu See allHide authors and affiliations Science Signaling 06 Apr 2010:Vol. 3, Issue 116, pp. ra28DOI: 10.1126/scisignal.2000593 Julien A. Sebag Department of Pharmacology and Physiology, University of Rochester Medical Center, Rochester, NY 14642, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site Patricia M. Hinkle Department of Pharmacology and Physiology, University of Rochester Medical Center, Rochester, NY 14642, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site For correspondence: Patricia_Hinkle@urmc.rochester.edu Article Figures & Data Info & Metrics eLetters PDF Article Information vol. 3 no. 116 ra28 DOI: https://doi.org/10.1126/scisignal.2000593 PubMed: 20371771 Published By: Science Signaling Print ISSN: 1945-0877 Online ISSN: 1937-9145 History: Received August 20, 2009Accepted March 19, 2010 . Copyright & Usage: Copyright © 2010, American Association for the Advancement of Science Author Information Altmetric Article usage Article lifetimeLast 6 monthsThis monthArticle usage: April 2010 to January 2021 AbstractFullPdf Apr 20101332170213 May 2010673024 Jun 2010382329 Jul 2010512412 Aug 2010103617 Sep 20106157 Oct 201058127 Nov 20103635 Dec 20105399 Jan 201144710 Feb 20114016 Mar 20113445 Apr 201137104 May 201137710 Jun 201119411 Jul 20112123 Aug 20112444 Sep 20113625 Oct 20112643 Nov 20111447 Dec 20112143 Jan 20123164 Feb 20122031 Mar 20122973 Apr 20121412 May 201234811 Jun 20122713 Jul 20122655 Aug 20122906 Sep 20122233 Oct 20122812 Nov 20121631 Dec 20121733 Jan 20133234 Feb 20131711 Mar 20133142 Apr 20132334 May 20133046 Jun 20133710 Jul 2013661119 Aug 201334810 Sep 201361804 Oct 20133163 Nov 20134344 Dec 20134744 Jan 20142744 Feb 20142645 Mar 20143687 Apr 20142754 May 20143236 Jun 20142737 Jul 20141774 Aug 20141502 Sep 20141142 Oct 2014932 Nov 20149105 Dec 2014611 Jan 20151013 Feb 20151165 Mar 20151500 Apr 201510612 May 20152044 Jun 20151137 Jul 2015100 Aug 2015302 Sep 2015703 Oct 2015302 Nov 20151014 Dec 20151021 Jan 20163013 Feb 20162014 Mar 20162614 Apr 20163023 May 20162121 Jun 20165010 Jul 20163642 Aug 20163312 Sep 20164203 Oct 20165625 Nov 20164725 Dec 20163120 Jan 20174024 Feb 20174956 Mar 20173110 Apr 20174000 May 20174013 Jun 20173113 Jul 20173922 Aug 20175112 Sep 20174435 Oct 20172543 Nov 20172320 Dec 20171411 Jan 20183125 Feb 20184222 Mar 20183032 Apr 20185281 May 20184010 Jun 20181411 Jul 20182213 Aug 20181431 Sep 20182124 Oct 20183033 Nov 20183162 Dec 20182130 Jan 20191752 Feb 20192711 Mar 20192352 Apr 2019940 May 2019843 Jun 20192243 Jul 20191621 Aug 2019730 Sep 2019441 Oct 201919114 Nov 20191675 Dec 20191942 Jan 202022120 Feb 2020832 Mar 202016118 Apr 20201840 May 202027294 Jun 20203131 Jul 20202364 Aug 20201263 Sep 20203262 Oct 20202894 Nov 20204312 Dec 202016103 Jan 20211129 View Full Text
Regulation of G Protein–Coupled Receptor Signaling: Specific Dominant-Negative Effects of Melanocortin 2 Receptor Accessory Protein 2 By Julien A. Sebag, Patricia M. Hinkle Science Signaling06 Apr 2010 : ra28 Two homologous accessory proteins exert opposing effects on the responsiveness of the melanocortin 2 receptor to the hormone ACTH.
Regulation of G Protein–Coupled Receptor Signaling: Specific Dominant-Negative Effects of Melanocortin 2 Receptor Accessory Protein 2 By Julien A. Sebag, Patricia M. Hinkle Science Signaling06 Apr 2010 : ra28 Two homologous accessory proteins exert opposing effects on the responsiveness of the melanocortin 2 receptor to the hormone ACTH.