11 May 2010
Vol 3, Issue 121

About The Cover

Cover image expansion

Online Cover This week's issue features a Research Article that shows that intracellular vesicles containing the transmembrane adaptor protein LAT migrate to and interact with protein microclusters at the interface between a T cell and an antigen-presenting cell. The image shows vesicular LAT (red) and microclusters containing the T cell receptor–associated kinase ZAP-70 (green) at the interface between a Jurkat T cell and a coverslip coated with an activating antibody. [Image: Marco Purbhoo, Imperial College London, UK]