Contents
Vol 3, Issue 131
Contents
Research Article
- Increased Abundance of Opioid Receptor Heteromers After Chronic Morphine Administration
The μ-δ opioid heteromer may be a target for alleviation of chronic pain.
Letters
- Comment on “Increased MKK4 Abundance with Replicative Senescence Is Linked to the Joint Reduction of Multiple MicroRNAs”
The antibody used to detect phosphorylated PRAK is suspect.
- Response to Comment on “Increased MKK4 Abundance with Replicative Senescence Is Linked to the Joint Reduction of Multiple MicroRNAs”
The antibody used to detect phosphorylated PRAK is suspect.
Podcast
- Science Signaling Podcast: 20 July 2010
Network redundancies lend robustness to the neuronal injury response.
Editors' Choice
- Stimulate the Mind, Fight Cancer
Enriched housing environments activate a brain-adipocyte signaling axis in mice that decreases tumor burden and incidence.
- Good ROS Versus Bad ROS
Opposite effects of chronic and acute oxidative stress are explained by distinct localization of a protein kinase and its regulatory phosphatase.
- Noncoding No More
A polycistronic RNA encodes multiple small peptides that regulate the activity of a transcription factor.
- Sending a Package Through the Blood
Secreted miRNAs may act as intercellular signaling molecules.
- Inhibiting Adhesion
Interferon-γ inhibits cell spreading by increasing the abundance of an unusual guanosine triphosphatase, GBP-2, that inhibits phosphoinositide 3-kinase.
- It Runs in the Family
Hh signaling in body segment formation suggests that annelids and arthropods may share a common segmented ancestor.
- Sulfur Signal Dinner
A microfluidics device reveals a common response of bacterial plankton to sulfur compounds emitted by marine algae.
