Research ArticleCOMPUTATIONAL BIOLOGY

Decoupling of Receptor and Downstream Signals in the Akt Pathway by Its Low-Pass Filter Characteristics

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Science Signaling  27 Jul 2010:
Vol. 3, Issue 132, pp. ra56
DOI: 10.1126/scisignal.2000810

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  • Decoupling of Receptor and Downstream Signals in the Akt Pathway by Its Low-Pass Filter Characteristics

    By Kazuhiro A. Fujita, Yu Toyoshima, Shinsuke Uda, Yu-ichi Ozaki, Hiroyuki Kubota, Shinya Kuroda

    Science Signaling : ra56

    The Akt pathway can serve as a signal decoupler, converting a weak receptor signal into a strong effector signal.

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