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Research ArticleImmunology
The Nonphagocytic NADPH Oxidase Duox1 Mediates a Positive Feedback Loop During T Cell Receptor Signaling
- Jaeyul Kwon1,2,*,
- Kristen E. Shatynski1,
- Haiyan Chen1,
- Stanislas Morand2,
- Xavier de Deken3,
- Françoise Miot3,
- Thomas L. Leto2, and
- Mark S. Williams1,*
- 1Center for Vascular and Inflammatory Diseases, Department of Microbiology and Immunology, University of Maryland School of Medicine, 800 West Baltimore Street, Baltimore, MD 21201, USA.
- 2Laboratory of Host Defenses, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 12441 Parklawn Drive, Rockville, MD 20852, USA.
- 3Institut de Recherche Interdisciplinaire en Biologie Humaine et Moléculaire, Université Libre de Bruxelles, Campus Erasme, 1070 Brussels, Belgium.
- ↵*To whom correspondence should be addressed. E-mail: marwilliams{at}som.umaryland.edu (M.S.W.); kwonja{at}niaid.nih.gov (J.K.)
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Science Signaling 03 Aug 2010:
Vol. 3, Issue 133, pp. ra59
DOI: 10.1126/scisignal.2000976
Vol. 3, Issue 133, pp. ra59
DOI: 10.1126/scisignal.2000976
Jaeyul Kwon
1Center for Vascular and Inflammatory Diseases, Department of Microbiology and Immunology, University of Maryland School of Medicine, 800 West Baltimore Street, Baltimore, MD 21201, USA.
2Laboratory of Host Defenses, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 12441 Parklawn Drive, Rockville, MD 20852, USA.
Kristen E. Shatynski
1Center for Vascular and Inflammatory Diseases, Department of Microbiology and Immunology, University of Maryland School of Medicine, 800 West Baltimore Street, Baltimore, MD 21201, USA.
Haiyan Chen
1Center for Vascular and Inflammatory Diseases, Department of Microbiology and Immunology, University of Maryland School of Medicine, 800 West Baltimore Street, Baltimore, MD 21201, USA.
Stanislas Morand
2Laboratory of Host Defenses, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 12441 Parklawn Drive, Rockville, MD 20852, USA.
Xavier de Deken
3Institut de Recherche Interdisciplinaire en Biologie Humaine et Moléculaire, Université Libre de Bruxelles, Campus Erasme, 1070 Brussels, Belgium.
Françoise Miot
3Institut de Recherche Interdisciplinaire en Biologie Humaine et Moléculaire, Université Libre de Bruxelles, Campus Erasme, 1070 Brussels, Belgium.
Thomas L. Leto
2Laboratory of Host Defenses, National Institute of Allergy and Infectious Diseases, National Institutes of Health, 12441 Parklawn Drive, Rockville, MD 20852, USA.
Mark S. Williams
1Center for Vascular and Inflammatory Diseases, Department of Microbiology and Immunology, University of Maryland School of Medicine, 800 West Baltimore Street, Baltimore, MD 21201, USA.
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