Self-Induced Patched Receptor Down-Regulation Modulates Cell Sensitivity to the Hedgehog Morphogen Gradient

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  Self-Induced Patched Receptor Down-Regulation Modulates Cell Sensitivity to the Hedgehog Morphogen Gradient

  By Andreu Casali

  Science Signaling24 Aug 2010 : ra63

  A self-regulating receptor allows cells to maintain the appropriate balance of ligand-bound and unbound receptors.

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  Self-Induced Patched Receptor Down-Regulation Modulates Cell Sensitivity to the Hedgehog Morphogen Gradient

  By Andreu Casali

  Science Signaling24 Aug 2010 : ra63

  A self-regulating receptor allows cells to maintain the appropriate balance of ligand-bound and unbound receptors.

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