Research ArticleBiophysics

Coupling Mechanism of a GPCR and a Heterotrimeric G Protein During Chemoattractant Gradient Sensing in Dictyostelium

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Science Signaling  28 Sep 2010:
Vol. 3, Issue 141, pp. ra71
DOI: 10.1126/scisignal.2000980

Article Information

vol. 3 no. 141 ra71

DOI: 
https://doi.org/10.1126/scisignal.2000980
PubMed: 
20876874
Published By: 
Science Signaling
Print ISSN: 
1945-0877
Online ISSN: 
1937-9145
History: 
  • Received March 8, 2010
  • Accepted September 10, 2010
  • .
Copyright & Usage: 
Copyright © 2010, American Association for the Advancement of Science

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  • Coupling Mechanism of a GPCR and a Heterotrimeric G Protein During Chemoattractant Gradient Sensing in Dictyostelium

    By Xuehua Xu, Tobias Meckel, Joseph A. Brzostowski, Jianshe Yan, Martin Meier-Schellersheim, Tian Jin

    Science Signaling : ra71

    Imaging analyses and computer simulations suggest that a GPCR and its G protein associate only in the presence of ligand.

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