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Research ArticleCell Biology
Genome-Wide RNAi Screen Reveals Disease-Associated Genes That Are Common to Hedgehog and Wnt Signaling
- Leni S. Jacob1,
- Xiaofeng Wu1,
- Michael E. Dodge1,
- Chih-Wei Fan1,
- Ozlem Kulak1,
- Baozhi Chen1,
- Wei Tang1,*,
- Baolin Wang2,3,
- James F. Amatruda4,5, and
- Lawrence Lum1,†
- 1Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
- 2Department of Cell and Developmental Biology, Weill Cornell Medical College, New York, NY 10065, USA.
- 3Department of Genetic Medicine, Weill Cornell Medical College, New York, NY 10065, USA.
- 4Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
- 5Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
- ↵†To whom correspondence should be addressed. E-mail: lawrence.lum{at}UTSouthwestern.edu
-
↵* Present address: BioDuro Co. Ltd., No. 29 Building, Life Science Park Road, Changping District, 102206 Beijing, People’s Republic of China.
See allHide authors and affiliations
Science Signaling 25 Jan 2011:
Vol. 4, Issue 157, pp. ra4
DOI: 10.1126/scisignal.2001225
Vol. 4, Issue 157, pp. ra4
DOI: 10.1126/scisignal.2001225
Leni S. Jacob
1Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Xiaofeng Wu
2Department of Cell and Developmental Biology, Weill Cornell Medical College, New York, NY 10065, USA.
Michael E. Dodge
1Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Chih-Wei Fan
1Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Ozlem Kulak
1Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Baozhi Chen
1Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Wei Tang
1Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Baolin Wang
2Department of Cell and Developmental Biology, Weill Cornell Medical College, New York, NY 10065, USA.
3Department of Genetic Medicine, Weill Cornell Medical College, New York, NY 10065, USA.
James F. Amatruda
4Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
5Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Lawrence Lum
1Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
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