Contents

Contents

• Research Articles

  • Wnt Signaling Regulates Hepatic Metabolism

    By Hongjun Liu, Maria M. Fergusson, J. Julie Wu, Ilsa I. Rovira, Jie Liu, Oksana Gavrilova, Teng Lu, Jianjun Bao, Donghe Han, Michael N. Sack, Toren Finkel

    Science Signaling01 Feb 2011 : ra6 Full AccessRestricted Access

    Nutrient deprivation triggers β-catenin–dependent expression of genes encoding gluconeogenic enzymes.

    • Editor's Summary
    • Abstract
    • Full Text
    • PDF

  • Mitochondrial Membrane Potential Is Required for MAVS-Mediated Antiviral Signaling

    By Takumi Koshiba, Kai Yasukawa, Yusuke Yanagi, Shun-ichiro Kawabata

    Science Signaling01 Feb 2011 : ra7 Full AccessRestricted Access

    The contribution of mitochondria to antiviral immune responses extends beyond their role as a platform for antiviral signaling molecules.

    • Editor's Summary
    • Abstract
    • Full Text
    • PDF

• Perspective

  • To Be or Not to Be a T_reg Cell: Lineage Decisions Controlled by Epigenetic Mechanisms

    By Aras Toker, Jochen Huehn

    Science Signaling01 Feb 2011 : pe4 Full AccessRestricted Access

    Differentiation of natural regulatory T cells is restricted by the SUMO ligase PIAS1.

    • Abstract
    • Full Text
    • PDF

• Editors' Choice

  • Free from Transcription

    By John F. Foley

    Science Signaling01 Feb 2011 : ec29 Full AccessRestricted Access

    Circadian rhythms in humans and algae can occur without the need for transcription-translation feedback control.

    • Abstract

  • Flipping for Opsin

    By Elizabeth M. Adler

    Science Signaling01 Feb 2011 : ec30 Full AccessRestricted Access

    The G protein–coupled receptor opsin acts as a phospholipid flippase.

    • Abstract

  • Are You Experienced?

    By Wei Wong

    Science Signaling01 Feb 2011 : ec31 Full AccessRestricted Access

    In naïve and experienced human T cells, activation of the TCR elicits different signaling pathways.

    • Abstract

  • MALT Lymphomagenesis Revisited

    By Kristen L. Mueller

    Science Signaling01 Feb 2011 : ec32 Full AccessRestricted Access

    An oncogenic fusion protein promotes lymphomagenesis by activating a noncanonical signaling pathway.

    • Abstract

  • So Hungry I Could Eat Myself

    By L. Bryan Ray

    Science Signaling01 Feb 2011 : ec33 Full AccessRestricted Access

    A protein kinase links energy stores to control of autophagy.

    • Abstract

  • Parasite Replication Trigger

    By Stella M. Hurtley

    Science Signaling01 Feb 2011 : ec34 Full AccessRestricted Access

    Membrane proteins govern a change from invasion to replication of an intracellular parasite.

    • Abstract