Contents
Vol 4, Issue 158
Contents
Research Articles
- Wnt Signaling Regulates Hepatic Metabolism
Nutrient deprivation triggers β-catenin–dependent expression of genes encoding gluconeogenic enzymes.
- Mitochondrial Membrane Potential Is Required for MAVS-Mediated Antiviral Signaling
The contribution of mitochondria to antiviral immune responses extends beyond their role as a platform for antiviral signaling molecules.
Perspective
- To Be or Not to Be a Treg Cell: Lineage Decisions Controlled by Epigenetic Mechanisms
Differentiation of natural regulatory T cells is restricted by the SUMO ligase PIAS1.
Editors' Choice
- Free from Transcription
Circadian rhythms in humans and algae can occur without the need for transcription-translation feedback control.
- Are You Experienced?
In naïve and experienced human T cells, activation of the TCR elicits different signaling pathways.
- MALT Lymphomagenesis Revisited
An oncogenic fusion protein promotes lymphomagenesis by activating a noncanonical signaling pathway.
- Parasite Replication Trigger
Membrane proteins govern a change from invasion to replication of an intracellular parasite.