Wnt Signaling Regulates Hepatic Metabolism

Hongjun Liu; Maria M. Fergusson; J. Julie Wu; Ilsa I. Rovira; Jie Liu; Oksana Gavrilova; Teng Lu; Jianjun Bao; Donghe Han; Michael N. Sack; Toren Finkel

doi:10.1126/scisignal.2001249

Research ArticleMetabolism

Wnt Signaling Regulates Hepatic Metabolism

Hongjun Liu¹,*,
Maria M. Fergusson¹,
J. Julie Wu¹,
Ilsa I. Rovira¹,
Jie Liu¹,
Oksana Gavrilova²,
Teng Lu¹,³,
Jianjun Bao¹,
Donghe Han⁴,
Michael N. Sack¹, and
Toren Finkel¹,†

¹Center for Molecular Medicine, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.
²Mouse Metabolism Core, National Institute of Diabetes and Digestive and Kidney Disease, National Institutes of Health, Bethesda, MD 20892, USA.
³Emory University School of Medicine, Atlanta, GA 30322, USA.
⁴Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219, USA.

↵†To whom correspondence should be addressed. E-mail: finkelt{at}nih.gov

↵* Present address: Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219, USA.

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Science Signaling 01 Feb 2011:
Vol. 4, Issue 158, pp. ra6
DOI: 10.1126/scisignal.2001249

Hongjun Liu

1Center for Molecular Medicine, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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Maria M. Fergusson

1Center for Molecular Medicine, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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J. Julie Wu

1Center for Molecular Medicine, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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Ilsa I. Rovira

1Center for Molecular Medicine, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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Jie Liu

1Center for Molecular Medicine, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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Oksana Gavrilova

2Mouse Metabolism Core, National Institute of Diabetes and Digestive and Kidney Disease, National Institutes of Health, Bethesda, MD 20892, USA.

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Teng Lu

1Center for Molecular Medicine, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.

3Emory University School of Medicine, Atlanta, GA 30322, USA.

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Jianjun Bao

1Center for Molecular Medicine, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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Donghe Han

4Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15219, USA.

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Michael N. Sack

1Center for Molecular Medicine, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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Toren Finkel

1Center for Molecular Medicine, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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For correspondence: finkelt@nih.gov

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Wnt Signaling Regulates Hepatic Metabolism

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