Contents
Vol 4, Issue 162
Contents
Research Article
- ATP Inhibits the Generation and Function of Regulatory T Cells Through the Activation of Purinergic P2X Receptors
Purinergic signaling during inflammation converts immunosuppressive CD4+ T cells into proinflammatory ones.
Perspective
- Astrocytes Shape Axonal Signaling
The action potential waveform can be altered by astrocyte-mediated activation of neuronal glutamate receptors.
Editors' Choice
- Terms of Disengagement
To prevent destruction of self, inhibitory receptors block clustering of activating receptors and cause natural killer cells to disengage.
- Tregs Promote Metastasis
Receptor activator of nuclear factor κB ligand (RANKL) produced by regulatory T cells triggers the metastasis of breast cancer cells.
- Touch Off a Fight
A contact pheromone produced by females induces aggression in male squid.
- Sphingolipids and Retinal Degeneration
Too much dihydrosphingosine 1-phosphate enhances degradation of photoreceptor membrane proteins and leads to retinal degeneration in flies.
- Reaching a Quorum Isn’t Simple
AphA and LuxR are opposing forces in the Vibrio quorum sensing pathway.
