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vol. 4 no. 170 ra26
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- Received April 28, 2010
- Accepted April 6, 2011
- .
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Copyright © 2011, American Association for the Advancement of Science
Research ArticleNeuroscience
Thioredoxin Mediates Oxidation-Dependent Phosphorylation of CRMP2 and Growth Cone Collapse
- Akifumi Morinaka1,
- Mayumi Yamada2,3,
- Rurika Itofusa4,
- Yosuke Funato1,
- Yuta Yoshimura1,
- Fumio Nakamura5,
- Takeshi Yoshimura6,*,
- Kozo Kaibuchi6,
- Yoshio Goshima5,
- Mikio Hoshino2,
- Hiroyuki Kamiguchi4, and
- Hiroaki Miki1,†
- 1Laboratory of Intracellular Signaling, Institute for Protein Research, Osaka University, 3-2 Yamadaoka, Suita, Osaka 565-0871, Japan.
- 2Department of Biochemistry and Cellular Biology, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira, Tokyo 187-8502, Japan.
- 3Department of Pathology and Tumor Biology, Kyoto University Graduate School of Medicine, Sakyo-ku, Kyoto 606-8501, Japan.
- 4Laboratory for Neuronal Growth Mechanisms, RIKEN Brain Science Institute, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.
- 5Department of Molecular Pharmacology and Neurobiology, Graduate School of Medicine, Yokohama City University, Yokohama, Kanagawa 236-0004, Japan.
- 6Department of Cell Pharmacology, Graduate School of Medicine, Nagoya University, 65 Tsurumai, Showa, Nagoya, Aichi 466-8550, Japan.
- ↵†To whom correspondence should be addressed. E-mail: hmiki{at}protein.osaka-u.ac.jp
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↵* Present address: Division of Neurobiology and Bioinformatics, National Institute for Physiological Sciences, Institutes of Natural Sciences, 5-1 Higashiyama, Myodaiji, Okazaki, Aichi 444-8787, Japan.
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Science Signaling 26 Apr 2011:
Vol. 4, Issue 170, pp. ra26
DOI: 10.1126/scisignal.2001127
Vol. 4, Issue 170, pp. ra26
DOI: 10.1126/scisignal.2001127
Akifumi Morinaka
1Laboratory of Intracellular Signaling, Institute for Protein Research, Osaka University, 3-2 Yamadaoka, Suita, Osaka 565-0871, Japan.
Mayumi Yamada
2Department of Biochemistry and Cellular Biology, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira, Tokyo 187-8502, Japan.
3Department of Pathology and Tumor Biology, Kyoto University Graduate School of Medicine, Sakyo-ku, Kyoto 606-8501, Japan.
Rurika Itofusa
4Laboratory for Neuronal Growth Mechanisms, RIKEN Brain Science Institute, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.
Yosuke Funato
1Laboratory of Intracellular Signaling, Institute for Protein Research, Osaka University, 3-2 Yamadaoka, Suita, Osaka 565-0871, Japan.
Yuta Yoshimura
1Laboratory of Intracellular Signaling, Institute for Protein Research, Osaka University, 3-2 Yamadaoka, Suita, Osaka 565-0871, Japan.
Fumio Nakamura
5Department of Molecular Pharmacology and Neurobiology, Graduate School of Medicine, Yokohama City University, Yokohama, Kanagawa 236-0004, Japan.
Takeshi Yoshimura
6Department of Cell Pharmacology, Graduate School of Medicine, Nagoya University, 65 Tsurumai, Showa, Nagoya, Aichi 466-8550, Japan.
Kozo Kaibuchi
6Department of Cell Pharmacology, Graduate School of Medicine, Nagoya University, 65 Tsurumai, Showa, Nagoya, Aichi 466-8550, Japan.
Yoshio Goshima
5Department of Molecular Pharmacology and Neurobiology, Graduate School of Medicine, Yokohama City University, Yokohama, Kanagawa 236-0004, Japan.
Mikio Hoshino
2Department of Biochemistry and Cellular Biology, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira, Tokyo 187-8502, Japan.
Hiroyuki Kamiguchi
4Laboratory for Neuronal Growth Mechanisms, RIKEN Brain Science Institute, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.
Hiroaki Miki
1Laboratory of Intracellular Signaling, Institute for Protein Research, Osaka University, 3-2 Yamadaoka, Suita, Osaka 565-0871, Japan.
