Research ArticleChannels TWIK-1 Two-Pore Domain Potassium Channels Change Ion Selectivity and Conduct Inward Leak Sodium Currents in Hypokalemia Liqun Ma, Xuexin Zhang, and Haijun Chen*Department of Biological Sciences, University at Albany, State University of New York, Albany, NY 12222, USA.↵*To whom correspondence should be addressed. E-mail: hchen01{at}albany.edu See allHide authors and affiliations Science Signaling 07 Jun 2011:Vol. 4, Issue 176, pp. ra37DOI: 10.1126/scisignal.2001726 Liqun Ma Department of Biological Sciences, University at Albany, State University of New York, Albany, NY 12222, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site Xuexin Zhang Department of Biological Sciences, University at Albany, State University of New York, Albany, NY 12222, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site Haijun Chen Department of Biological Sciences, University at Albany, State University of New York, Albany, NY 12222, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site For correspondence: hchen01@albany.edu Article Figures & Data Info & Metrics eLetters PDF Article Information vol. 4 no. 176 ra37 DOI: https://doi.org/10.1126/scisignal.2001726 PubMed: 21653227 Published By: Science Signaling Print ISSN: 1945-0877 Online ISSN: 1937-9145 History: Received November 30, 2010Accepted May 18, 2011 . Copyright & Usage: Copyright © 2011, American Association for the Advancement of Science Author Information Altmetric Article usage Article lifetimeLast 6 monthsThis monthArticle usage: June 2011 to January 2021 AbstractFullPdf Jun 20112290134178 Jul 20113073038 Aug 20114084986 Sep 20111521131 Oct 20111391723 Nov 20111021227 Dec 20118698 Jan 20121132123 Feb 20121121720 Mar 2012843028 Apr 20121043316 May 20121262124 Jun 2012761314 Jul 201270923 Aug 2012811122 Sep 2012841129 Oct 2012901133 Nov 2012751420 Dec 2012811920 Jan 2013742022 Feb 201347136 Mar 2013481110 Apr 20133799 May 2013451514 Jun 2013501314 Jul 20136088 Aug 20133673 Sep 201366129 Oct 2013802218 Nov 2013551210 Dec 2013431110 Jan 20144787 Feb 2014451510 Mar 20148157 Apr 20146586 May 20148565 Jun 20147969 Jul 20145644 Aug 20143285 Sep 2014302118 Oct 2014271913 Nov 201446129 Dec 20142955 Jan 20153582 Feb 201521911 Mar 20151354770 Apr 201525711 May 20152744 Jun 20159005 Jul 201556710 Aug 2015225 Sep 20156717 Oct 201571112 Nov 2015947 Dec 20151646 Jan 20163625 Feb 20163215 Mar 20165016 Apr 201664103 May 20164424 Jun 20169039 Jul 20169299 Aug 20166954 Sep 20166406 Oct 20166732 Nov 20167347 Dec 20164710 Jan 20174575 Feb 20176967 Mar 2017142513 Apr 201781103 May 201770118 Jun 20173945 Jul 20176733 Aug 20175213 Sep 20172838 Oct 20175923 Nov 20176064 Dec 20176611 Jan 20189587 Feb 20186742 Mar 20185889 Apr 201841118 May 20184696 Jun 20183711 Jul 20184487 Aug 20183484 Sep 20183563 Oct 20183861 Nov 201871123 Dec 20183752 Jan 20193392 Feb 201939115 Mar 201931136 Apr 20193983 May 201941168 Jun 201927185 Jul 201932114 Aug 201938186 Sep 20192071 Oct 201921178 Nov 20193173 Dec 201926103 Jan 20202191 Feb 202020112 Mar 20201783 Apr 20202052 May 202018137 Jun 20201791 Jul 202015103 Aug 2020880 Sep 202021116 Oct 202028166 Nov 20202772 Dec 20202882 Jan 20211194 View Full Text
TWIK-1 Two-Pore Domain Potassium Channels Change Ion Selectivity and Conduct Inward Leak Sodium Currents in Hypokalemia By Liqun Ma, Xuexin Zhang, Haijun Chen Science Signaling07 Jun 2011 : ra37 Very low extracellular K+ concentrations, which can trigger cardiac arrhythmias, cause TWIK-1 potassium channels to become permeable to Na+.
TWIK-1 Two-Pore Domain Potassium Channels Change Ion Selectivity and Conduct Inward Leak Sodium Currents in Hypokalemia By Liqun Ma, Xuexin Zhang, Haijun Chen Science Signaling07 Jun 2011 : ra37 Very low extracellular K+ concentrations, which can trigger cardiac arrhythmias, cause TWIK-1 potassium channels to become permeable to Na+.