Antigen Potency and Maximal Efficacy Reveal a Mechanism of Efficient T Cell Activation

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  Antigen Potency and Maximal Efficacy Reveal a Mechanism of Efficient T Cell Activation

  By Omer Dushek, Milos Aleksic, Richard J. Wheeler, Hao Zhang, Shaun-Paul Cordoba, Yan-Chun Peng, Ji-Li Chen, Vincenzo Cerundolo, Tao Dong, Daniel Coombs, Philip Anton van der Merwe

  Science Signaling07 Jun 2011 : ra39

  Efficient T cell activation depends on the rate with which T cell receptors and antigens bind and unbind, rather than simply their equilibrium affinity.

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  Antigen Potency and Maximal Efficacy Reveal a Mechanism of Efficient T Cell Activation

  By Omer Dushek, Milos Aleksic, Richard J. Wheeler, Hao Zhang, Shaun-Paul Cordoba, Yan-Chun Peng, Ji-Li Chen, Vincenzo Cerundolo, Tao Dong, Daniel Coombs, Philip Anton van der Merwe

  Science Signaling07 Jun 2011 : ra39

  Efficient T cell activation depends on the rate with which T cell receptors and antigens bind and unbind, rather than simply their equilibrium affinity.

  • Supplementary Materials

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