Research ArticleCancer Biology
TRPS1 Targeting by miR-221/222 Promotes the Epithelial-to-Mesenchymal Transition in Breast Cancer
- Susanna Stinson1,*,
- Mark R. Lackner2,*,
- Alex T. Adai3,*,
- Nancy Yu1,
- Hyo-Jin Kim1,
- Carol O’Brien2,
- Jill Spoerke2,
- Suchit Jhunjhunwala4,
- Zachary Boyd2,
- Thomas Januario1,
- Robert J. Newman5,
- Peng Yue4,
- Richard Bourgon4,
- Zora Modrusan5,
- Howard M. Stern6,
- Søren Warming5,
- Frederic J. de Sauvage5,
- Lukas Amler2,
- Ru-Fang Yeh7, and
- David Dornan1,†
- 1Department of Molecular Diagnostics and Cancer Cell Biology, Genentech Inc., South San Francisco, CA 94080, USA.
- 2Department of Development Oncology Diagnostics, Genentech Inc., South San Francisco, CA 94080, USA.
- 3Center for Bioinformatics and Molecular Biostatistics, University of California, San Francisco, CA 94143, USA.
- 4Department of Bioinformatics, Genentech Inc., South San Francisco, CA 94080, USA.
- 5Department of Molecular Biology, Genentech Inc., South San Francisco, CA 94080, USA.
- 6Department of Pathology, Genentech Inc., South San Francisco, CA 94080, USA.
- 7Department of Biostatistics, Genentech Inc., South San Francisco, CA 94080, USA.
- ↵†To whom correspondence should be addressed. E-mail: dornan.david{at}gene.com
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Science Signaling 14 Jun 2011:
Vol. 4, Issue 177, pp. ra41
DOI: 10.1126/scisignal.2001538
