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Research ArticleSensory Perception
The Distinct Roles of Two GPCRs, MrgprC11 and PAR2, in Itch and Hyperalgesia
- Qin Liu1,*,
- Hao-Jui Weng1,*,
- Kush N. Patel1,*,
- Zongxiang Tang1,2,
- Haihua Bai1,3,
- Martin Steinhoff4,5, and
- Xinzhong Dong1,6,†
- 1Solomon H. Snyder Department of Neuroscience, Center for Sensory Biology, Johns Hopkins University School of Medicine, 725 North Wolfe Street, Baltimore, MD 21205, USA.
- 2Nanjing University of Chinese Medicine, 138 Xianlin Road, Nanjing 210046, China.
- 3Inner Mongolia University for the Nationalities, School of Life Science, 22 Huolinhe Street, Tongliao City 028043, China.
- 4Department of Dermatology, University of California, San Francisco, CA 94143, USA.
- 5Department of Surgery, University of California, San Francisco, CA 94143, USA.
- 6Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
- ↵†To whom correspondence should be addressed. E-mail: xdong2{at}jhmi.edu
-
↵* These authors contributed equally to this work.
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Science Signaling 12 Jul 2011:
Vol. 4, Issue 181, pp. ra45
DOI: 10.1126/scisignal.2001925
Vol. 4, Issue 181, pp. ra45
DOI: 10.1126/scisignal.2001925
Qin Liu
1Solomon H. Snyder Department of Neuroscience, Center for Sensory Biology, Johns Hopkins University School of Medicine, 725 North Wolfe Street, Baltimore, MD 21205, USA.
Hao-Jui Weng
1Solomon H. Snyder Department of Neuroscience, Center for Sensory Biology, Johns Hopkins University School of Medicine, 725 North Wolfe Street, Baltimore, MD 21205, USA.
Kush N. Patel
1Solomon H. Snyder Department of Neuroscience, Center for Sensory Biology, Johns Hopkins University School of Medicine, 725 North Wolfe Street, Baltimore, MD 21205, USA.
Zongxiang Tang
1Solomon H. Snyder Department of Neuroscience, Center for Sensory Biology, Johns Hopkins University School of Medicine, 725 North Wolfe Street, Baltimore, MD 21205, USA.
2Nanjing University of Chinese Medicine, 138 Xianlin Road, Nanjing 210046, China.
Haihua Bai
1Solomon H. Snyder Department of Neuroscience, Center for Sensory Biology, Johns Hopkins University School of Medicine, 725 North Wolfe Street, Baltimore, MD 21205, USA.
3Inner Mongolia University for the Nationalities, School of Life Science, 22 Huolinhe Street, Tongliao City 028043, China.
Martin Steinhoff
4Department of Dermatology, University of California, San Francisco, CA 94143, USA.
5Department of Surgery, University of California, San Francisco, CA 94143, USA.
Xinzhong Dong
1Solomon H. Snyder Department of Neuroscience, Center for Sensory Biology, Johns Hopkins University School of Medicine, 725 North Wolfe Street, Baltimore, MD 21205, USA.
6Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
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