Contents
Vol 4, Issue 186
Contents
Research Article
- Yeast Dynamically Modify Their Environment to Achieve Better Mating Efficiency
By reshaping the pheromone gradient through proteolysis, yeast find partners of the opposite “sex” for mating.
Presentation
- miR-221/222 Targeting of Trichorhinophalangeal 1 (TRPS1) Promotes Epithelial-to-Mesenchymal Transition in Breast Cancer
MicroRNAs miR-221 and miR-222 are associated with a clinically aggressive form of breast cancer and promote epithelial-to-mesenchymal transition.
Editors' Choice
- The Duality of Kif7
Kif7 exerts both positive and negative control over hedgehog signaling through its regulation of Gli transcription factors.
- Add Lipidation to Histone Modifications
Calcium triggers the nuclear translocation of the acyltransferase Lpcat1, where it mediates O-palmitoylation of histone H4.
- Stress Relief
Stress activates p38α, which leads to enhanced surface abundance of a serotonin transporter and increased serotonin uptake.
- The Right Receptor for Attention
An important molecular mechanism involved in cognition has been unraveled.
- Defining Boundaries with Notch
Notch-mediated inhibition of the microRNA bantam helps to stabilize a compartment boundary by inhibiting cell proliferation and promoting actin polymerization.