23 August 2011
Vol 4, Issue 187

About The Cover

Cover image expansion

Online Cover This week features a Perspective that describes how phosphorylation of the autophagy adaptor optineurin by TBK1, a kinase involved in innate immune responses, limits the growth of a bacterial pathogen. The image shows a Salmonella bacterium in the initial stages of being engulfed by an autophagosome. [Image: Bricelyn Strauch, Science Signaling]