Research ArticleDevelopment
Regulation of Insulin-Like Growth Factor Signaling by Yap Governs Cardiomyocyte Proliferation and Embryonic Heart Size
- Mei Xin1,
- Yuri Kim1,
- Lillian B. Sutherland1,
- Xiaoxia Qi1,
- John McAnally1,
- Robert J. Schwartz2,3,
- James A. Richardson1,4,
- Rhonda Bassel-Duby1, and
- Eric N. Olson1,*
- 1Department of Molecular Biology, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75390–9148, USA.
- 2Texas Heart Institute, Texas Medical Center, Houston, TX 77030, USA.
- 3Department of Biology and Biochemistry, University of Houston, Houston, TX 77004, USA.
- 4Department of Pathology, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390–9148, USA.
- ↵*To whom correspondence should be addressed. E-mail: eric.olson{at}utsouthwestern.edu
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Science Signaling 25 Oct 2011:
Vol. 4, Issue 196, pp. ra70
DOI: 10.1126/scisignal.2002278
