LetterTheoretical Biology Comment on “Load-Induced Modulation of Signal Transduction Networks”: Reconciling Ultrasensitivity with Bifunctionality? Ronny Straube*Max Planck Institute for Dynamics of Complex Technical Systems, Sandtorstrasse 1, 39106 Magdeburg, Germany.↵*E-mail, rstraube{at}mpi-magdeburg.mpg.de; telephone, 0049-391-6110-481 See allHide authors and affiliations Science Signaling 03 Jan 2012:Vol. 5, Issue 205, pp. lc1DOI: 10.1126/scisignal.2002699 Ronny Straube Max Planck Institute for Dynamics of Complex Technical Systems, Sandtorstrasse 1, 39106 Magdeburg, Germany.Find this author on Google Scholar Find this author on PubMed Search for this author on this site For correspondence: rstraube@mpi-magdeburg.mpg.de Article Figures & Data Info & Metrics eLetters PDF Article Information vol. 5 no. 205 lc1 DOI: https://doi.org/10.1126/scisignal.2002699 PubMed: 22215730 Published By: Science Signaling Print ISSN: 1945-0877 Online ISSN: 1937-9145 History: . Copyright & Usage: Copyright © 2012, American Association for the Advancement of Science Author Information Ronny Straube*Max Planck Institute for Dynamics of Complex Technical Systems, Sandtorstrasse 1, 39106 Magdeburg, Germany.↵*E-mail, rstraube{at}mpi-magdeburg.mpg.de; telephone, 0049-391-6110-481 Altmetric Article usage Article lifetimeLast 6 monthsThis monthArticle usage: January 2012 to February 2021 AbstractFullPdf Jan 20123497263 Feb 201249711 Mar 201244611 Apr 2012481511 May 20122624 Jun 20122656 Jul 201223114 Aug 20121923 Sep 20122346 Oct 201227225 Nov 20122033 Dec 20123212 Jan 20134123 Feb 20132402 Mar 20132201 Apr 20131733 May 20131932 Jun 20132416 Jul 20132501 Aug 20132444 Sep 20131112 Oct 20131611 Nov 20131312 Dec 20132310 Jan 20142802 Feb 2014922 Mar 20141600 Apr 20141811 May 20142121 Jun 20142000 Jul 20141611 Aug 20142301 Sep 20141401 Oct 20141301 Nov 20141011 Dec 2014602 Jan 2015901 Feb 2015800 Mar 20151303 Apr 20152154 May 20151700 Jun 2015501 Jul 2015710 Aug 2015010 Sep 20152503 Oct 20151012 Nov 20152102 Dec 2015801 Jan 20161400 Feb 20161001 Mar 20161122 Apr 20161602 May 20161110 Jun 20163721 Jul 20162850 Aug 20161610 Sep 20161600 Oct 20161902 Nov 20162713 Dec 20161710 Jan 20172410 Feb 20175331 Mar 201713400 Apr 20179303 May 20176911 Jun 201710210 Jul 20174710 Aug 20178010 Sep 20175020 Oct 20178911 Nov 20175810 Dec 20177600 Jan 20189341 Feb 20186320 Mar 20184230 Apr 20182340 May 20182710 Jun 20182720 Jul 20181910 Aug 20182130 Sep 20182023 Oct 20181531 Nov 20181941 Dec 20182121 Jan 20191241 Feb 20191721 Mar 20192231 Apr 20194552 May 20192710 Jun 2019682 Jul 20191621 Aug 2019741 Sep 20191110 Oct 20193051 Nov 20192131 Dec 20192621 Jan 20201231 Feb 2020910 Mar 2020341 Apr 2020910 May 2020121 Jun 2020431 Jul 2020610 Aug 2020730 Sep 2020820 Oct 20201471 Nov 20201210 Dec 20201472 Jan 2021941 Feb 20211410 View Full Text
Comment on “Load-Induced Modulation of Signal Transduction Networks”: Reconciling Ultrasensitivity with Bifunctionality? By Ronny Straube Science Signaling03 Jan 2012 : lc1 Mathematical modeling of a bifunctional enzyme system fails to reproduce the experimentally observed ultrasensitivity of the system.
Comment on “Load-Induced Modulation of Signal Transduction Networks”: Reconciling Ultrasensitivity with Bifunctionality? By Ronny Straube Science Signaling03 Jan 2012 : lc1 Mathematical modeling of a bifunctional enzyme system fails to reproduce the experimentally observed ultrasensitivity of the system.