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Research ArticlesMicrobiology
A Phosphorylated Pseudokinase Complex Controls Cell Wall Synthesis in Mycobacteria
- Christine L. Gee1,*,
- Kadamba G. Papavinasasundaram2,*,
- Sloane R. Blair1,
- Christina E. Baer1,
- Arnold M. Falick3,
- David S. King3,
- Jennifer E. Griffin2,
- Harene Venghatakrishnan2,
- Andrew Zukauskas2,
- Jun-Rong Wei4,
- Rakesh K. Dhiman5,
- Dean C. Crick5,
- Eric J. Rubin4,
- Christopher M. Sassetti2,6,†, and
- Tom Alber1,†
- 1Department of Molecular and Cell Biology, QB3 Institute, University of California, Berkeley, Berkeley, CA 94720–3220, USA.
- 2Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA.
- 3Howard Hughes Medical Institute Mass Spectrometry Laboratory, University of California, Berkeley, Berkeley, CA 94720–3202, USA.
- 4Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA 02115, USA.
- 5Colorado State University Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, 1682 Campus Delivery, Fort Collins, CO 80523, USA.
- 6Howard Hughes Medical Institute, University of Massachusetts Medical School, Worcester, MA 01655, USA.
- ↵†To whom correspondence should be addressed. E-mail: christopher.sassetti{at}umassmed.edu (C.M.S.); tom{at}ucxray.berkeley.edu (T.A.)
-
↵* These authors contributed equally to this work.
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Science Signaling 24 Jan 2012:
Vol. 5, Issue 208, pp. ra7
DOI: 10.1126/scisignal.2002525
Vol. 5, Issue 208, pp. ra7
DOI: 10.1126/scisignal.2002525
Christine L. Gee
1Department of Molecular and Cell Biology, QB3 Institute, University of California, Berkeley, Berkeley, CA 94720–3220, USA.
Kadamba G. Papavinasasundaram
2Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA.
Sloane R. Blair
1Department of Molecular and Cell Biology, QB3 Institute, University of California, Berkeley, Berkeley, CA 94720–3220, USA.
Christina E. Baer
1Department of Molecular and Cell Biology, QB3 Institute, University of California, Berkeley, Berkeley, CA 94720–3220, USA.
Arnold M. Falick
3Howard Hughes Medical Institute Mass Spectrometry Laboratory, University of California, Berkeley, Berkeley, CA 94720–3202, USA.
David S. King
3Howard Hughes Medical Institute Mass Spectrometry Laboratory, University of California, Berkeley, Berkeley, CA 94720–3202, USA.
Jennifer E. Griffin
2Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA.
Harene Venghatakrishnan
2Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA.
Andrew Zukauskas
2Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA.
Jun-Rong Wei
4Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA 02115, USA.
Rakesh K. Dhiman
5Colorado State University Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, 1682 Campus Delivery, Fort Collins, CO 80523, USA.
Dean C. Crick
5Colorado State University Mycobacteria Research Laboratories, Department of Microbiology, Immunology and Pathology, 1682 Campus Delivery, Fort Collins, CO 80523, USA.
Eric J. Rubin
4Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA 02115, USA.
Christopher M. Sassetti
2Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA.
6Howard Hughes Medical Institute, University of Massachusetts Medical School, Worcester, MA 01655, USA.
Tom Alber
1Department of Molecular and Cell Biology, QB3 Institute, University of California, Berkeley, Berkeley, CA 94720–3220, USA.
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