PerspectiveImmunology

The STING in the Tail for Cytosolic DNA–Dependent Activation of IRF3

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Science Signaling  06 Mar 2012:
Vol. 5, Issue 214, pp. pe9
DOI: 10.1126/scisignal.2002919

Article Information

vol. 5 no. 214 pe9

DOI: 
https://doi.org/10.1126/scisignal.2002919
PubMed: 
22394560
Published By: 
Science Signaling
Print ISSN: 
1945-0877
Online ISSN: 
1937-9145
History: 
  • .
Copyright & Usage: 
Copyright © 2012, American Association for the Advancement of Science

Author Information

  1. Andrew Bowie*
  1. Immunology Research Centre, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland.
  1. ↵*Corresponding author. E-mail: agbowie{at}tcd.ie

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  • The STING in the Tail for Cytosolic DNA–Dependent Activation of IRF3

    By Andrew Bowie

    Science Signaling : pe9

    The adaptor STING recruits a kinase and a transcription factor to mediate the response to cytosolic DNA.

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