Direct Binding Between Orai1 and AC8 Mediates Dynamic Interplay Between Ca2+ and cAMP Signaling | Science Signaling

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vol. 5 no. 219 ra29

DOI:

https://doi.org/10.1126/scisignal.2002299

PubMed:

Published By:

Science Signaling

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History:

Received June 23, 2011
Accepted March 20, 2012
.

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Copyright © 2012, American Association for the Advancement of Science

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Science Signaling: 5 (219)

Science Signaling

Vol 5, Issue 219
10 April 2012

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Direct Binding Between Orai1 and AC8 Mediates Dynamic Interplay Between Ca²⁺ and cAMP Signaling

By Debbie Willoughby, Katy L. Everett, Michelle L. Halls, Jonathan Pacheco, Philipp Skroblin, Luis Vaca, Enno Klussmann, Dermot M. F. Cooper

Science Signaling10 Apr 2012 : ra29

A signaling complex enables the compartmentalized regulation of cyclic AMP signaling by calcium entering through a specific channel.

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Direct Binding Between Orai1 and AC8 Mediates Dynamic Interplay Between Ca²⁺ and cAMP Signaling

By Debbie Willoughby, Katy L. Everett, Michelle L. Halls, Jonathan Pacheco, Philipp Skroblin, Luis Vaca, Enno Klussmann, Dermot M. F. Cooper

Science Signaling10 Apr 2012 : ra29

A signaling complex enables the compartmentalized regulation of cyclic AMP signaling by calcium entering through a specific channel.

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