Research ArticleCancer Ras Stabilization Through Aberrant Activation of Wnt/β-Catenin Signaling Promotes Intestinal Tumorigenesis Woo-Jeong Jeong1,2,*, Juyong Yoon1,2,*, Jong-Chan Park1,2, Soung-Hoon Lee1,2, Seung-Hoon Lee1,3, Saluja Kaduwal1,2, Hoguen Kim4, Jong-Bok Yoon1,3, and Kang-Yell Choi1,2,†1Translational Research Center for Protein Function Control, Yonsei University, Seoul 120-749, Korea.2Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul 120-749, Korea.3Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul 120-749, Korea.4Department of Pathology, Center for Chronic Metabolic Disease, College of Medicine, Yonsei University, Seoul 120-749, Korea.↵†To whom correspondence should be addressed. E-mail: kychoi{at}yonsei.ac.kr ↵* These authors contributed equally to this work. See allHide authors and affiliations Science Signaling 10 Apr 2012:Vol. 5, Issue 219, pp. ra30DOI: 10.1126/scisignal.2002242 Woo-Jeong Jeong 1Translational Research Center for Protein Function Control, Yonsei University, Seoul 120-749, Korea.2Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul 120-749, Korea.Find this author on Google Scholar Find this author on PubMed Search for this author on this site Juyong Yoon 1Translational Research Center for Protein Function Control, Yonsei University, Seoul 120-749, Korea.2Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul 120-749, Korea.Find this author on Google Scholar Find this author on PubMed Search for this author on this site Jong-Chan Park 1Translational Research Center for Protein Function Control, Yonsei University, Seoul 120-749, Korea.2Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul 120-749, Korea.Find this author on Google Scholar Find this author on PubMed Search for this author on this site Soung-Hoon Lee 1Translational Research Center for Protein Function Control, Yonsei University, Seoul 120-749, Korea.2Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul 120-749, Korea.Find this author on Google Scholar Find this author on PubMed Search for this author on this site Seung-Hoon Lee 1Translational Research Center for Protein Function Control, Yonsei University, Seoul 120-749, Korea.3Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul 120-749, Korea.Find this author on Google Scholar Find this author on PubMed Search for this author on this site Saluja Kaduwal 1Translational Research Center for Protein Function Control, Yonsei University, Seoul 120-749, Korea.2Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul 120-749, Korea.Find this author on Google Scholar Find this author on PubMed Search for this author on this site Hoguen Kim 4Department of Pathology, Center for Chronic Metabolic Disease, College of Medicine, Yonsei University, Seoul 120-749, Korea.Find this author on Google Scholar Find this author on PubMed Search for this author on this site Jong-Bok Yoon 1Translational Research Center for Protein Function Control, Yonsei University, Seoul 120-749, Korea.3Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul 120-749, Korea.Find this author on Google Scholar Find this author on PubMed Search for this author on this site Kang-Yell Choi 1Translational Research Center for Protein Function Control, Yonsei University, Seoul 120-749, Korea.2Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul 120-749, Korea.Find this author on Google Scholar Find this author on PubMed Search for this author on this site For correspondence: kychoi@yonsei.ac.kr Article Figures & Data Info & Metrics eLetters PDF Article Information vol. 5 no. 219 ra30 DOI: https://doi.org/10.1126/scisignal.2002242 PubMed: 22494971 Published By: Science Signaling Print ISSN: 1945-0877 Online ISSN: 1937-9145 History: Received June 1, 2011Accepted March 23, 2012 . 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Ras Stabilization Through Aberrant Activation of Wnt/β-Catenin Signaling Promotes Intestinal Tumorigenesis By Woo-Jeong Jeong, Juyong Yoon, Jong-Chan Park, Soung-Hoon Lee, Seung-Hoon Lee, Saluja Kaduwal, Hoguen Kim, Jong-Bok Yoon, Kang-Yell Choi Science Signaling10 Apr 2012 : ra30 Crosstalk between the Wnt/β-catenin and the MAPK pathways contributes to colon cancer.
Ras Stabilization Through Aberrant Activation of Wnt/β-Catenin Signaling Promotes Intestinal Tumorigenesis By Woo-Jeong Jeong, Juyong Yoon, Jong-Chan Park, Soung-Hoon Lee, Seung-Hoon Lee, Saluja Kaduwal, Hoguen Kim, Jong-Bok Yoon, Kang-Yell Choi Science Signaling10 Apr 2012 : ra30 Crosstalk between the Wnt/β-catenin and the MAPK pathways contributes to colon cancer.