Research ResourceCell Biology
Quantitative Imaging of Epithelial Cell Scattering Identifies Specific Inhibitors of Cell Motility and Cell-Cell Dissociation
- Dinah Loerke1,*,†,
- Quint le Duc2,*,
- Iris Blonk2,
- Andre Kerstens1,‡,
- Emma Spanjaard2,
- Matthias Machacek1,§,
- Gaudenz Danuser1,¶∥, and
- Johan de Rooij1,2,∥
- 1Department of Cell Biology, Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
- 2Hubrecht Institute for Developmental Biology and Stem Cell Research, Uppsalalaan 8, 3584 CT Utrecht, Netherlands.
- ↵∥To whom correspondence should be addressed. E-mail: j.derooij{at}hubrecht.eu (J.d.R.); Gaudenz_Danuser{at}hms.harvard.edu (G.D.)
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↵* These authors contributed equally to this work.
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↵† Present address: Department of Physics and Astronomy, University of Denver, 2112 East Wesley Avenue, Denver, CO 80208, USA.
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↵‡ Present address: Penguin Computing Inc., 45800 Northport Loop West, Fremont, CA 94538, USA.
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↵§ Present address: Novartis Pharma AG, Lichtstrasse 35, CH-4056 Basel, Switzerland.
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↵¶ Present address: Department of Cell Biology, Harvard Medical School, 240 Longwood Avenue, Boston, MA 02115, USA.
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Science Signaling 03 Jul 2012:
Vol. 5, Issue 231, pp. rs5
DOI: 10.1126/scisignal.2002677