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vol. 5 no. 245 ra73
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History:
- Received May 11, 2012
- Accepted September 20, 2012
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Copyright © 2012, American Association for the Advancement of Science
Research ArticleVirology
Interferon-Induced SCYL2 Limits Release of HIV-1 by Triggering PP2A-Mediated Dephosphorylation of the Viral Protein Vpu
- Kei Miyakawa1,2,
- Tatsuya Sawasaki3,
- Satoko Matsunaga1,
- Andrey Tokarev4,
- Gary Quinn1,
- Hirokazu Kimura5,
- Masako Nomaguchi6,
- Akio Adachi6,
- Naoki Yamamoto7,
- John Guatelli4,8, and
- Akihide Ryo1,*
- 1Department of Microbiology, Yokohama City University School of Medicine, Kanagawa 236-0004, Japan.
- 2Japanese Foundation for AIDS Prevention, Tokyo 101-0061, Japan.
- 3Cell-Free Science and Technology Research Center, Ehime University, Ehime 790-8577, Japan.
- 4Department of Medicine, University of California, La Jolla, CA 92093, USA.
- 5Infectious Disease Surveillance Center, National Institute of Infectious Diseases, Tokyo 208-0011, Japan.
- 6Department of Microbiology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima 770-8503, Japan.
- 7Department of Microbiology, National University of Singapore, Singapore 117597, Singapore.
- 8San Diego Veterans Affairs Healthcare System, San Diego, CA 92161, USA.
- ↵*To whom correspondence should be addressed. E-mail: aryo{at}yokohama-cu.ac.jp
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Science Signaling 09 Oct 2012:
Vol. 5, Issue 245, pp. ra73
DOI: 10.1126/scisignal.2003212
Vol. 5, Issue 245, pp. ra73
DOI: 10.1126/scisignal.2003212
Kei Miyakawa
Department of Microbiology, Yokohama City University School of Medicine, Kanagawa 236-0004, Japan.
Japanese Foundation for AIDS Prevention, Tokyo 101-0061, Japan.
Tatsuya Sawasaki
Cell-Free Science and Technology Research Center, Ehime University, Ehime 790-8577, Japan.
Satoko Matsunaga
Department of Microbiology, Yokohama City University School of Medicine, Kanagawa 236-0004, Japan.
Andrey Tokarev
Department of Medicine, University of California, La Jolla, CA 92093, USA.
Gary Quinn
Department of Microbiology, Yokohama City University School of Medicine, Kanagawa 236-0004, Japan.
Hirokazu Kimura
Infectious Disease Surveillance Center, National Institute of Infectious Diseases, Tokyo 208-0011, Japan.
Masako Nomaguchi
Department of Microbiology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima 770-8503, Japan.
Akio Adachi
Department of Microbiology, Institute of Health Biosciences, The University of Tokushima Graduate School, Tokushima 770-8503, Japan.
Naoki Yamamoto
Department of Microbiology, National University of Singapore, Singapore 117597, Singapore.
John Guatelli
Department of Medicine, University of California, La Jolla, CA 92093, USA.
San Diego Veterans Affairs Healthcare System, San Diego, CA 92161, USA.
Akihide Ryo
Department of Microbiology, Yokohama City University School of Medicine, Kanagawa 236-0004, Japan.
