Contents
Vol 6, Issue 259
Contents
Research Articles
- Phosphoinositide 3-Kinase γ Inhibits Cardiac GSK-3 Independently of Akt
A kinase promotes cardiac hypertrophy through a kinase-independent mechanism.
- Systems Biology Approach Identifies the Kinase Csnk1a1 as a Regulator of the DNA Damage Response in Embryonic Stem Cells
Genotoxic stress induces Wnt signaling that attenuates apoptosis in embryonic stem cells.
Perspective
- The Hippo Size Control Pathway—Ever Expanding
More signals controlling the nuclear localization of YAP are identified.
Editors' Choice
- Signaling Differentiation
A molecular mechanism to inhibit Delta-Notch signaling and initiate neurogenesis is elucidated.
- Sonic Hedgehog Mediates Pathogen-Specific Response
Sonic hedgehog signaling modulates the immune response to Mycobacterium bovis.
- Controlling the Allergic Reaction
The alarmins Mrp8 and Mrp14 function as both activators and inhibitors of the immune response.
- Nitrosylation Promotes AMPA Receptor Phosphorylation
S-Nitrosylation of an AMPA receptor subunit contributes to activity-dependent regulation in channel activity.
- Defeat, Distress, and Glucocorticoids
Social stress can act through glucocorticoids on discrete dopamine-controlled neuronal pathways in the rodent brain to influence behavior.
- A Well-Defined Path
In mouse skin, immune cells migrate toward lymphatic vessels along an immobilized chemokine gradient.