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Research ArticleMICRORNAs
Signaling by p38 MAPK Stimulates Nuclear Localization of the Microprocessor Component p68 for Processing of Selected Primary MicroRNAs
- Sungguan Hong1,*,
- Hyangsoon Noh1,*,
- Haoming Chen2,
- Ravi Padia1,
- Zhixing K. Pan3,
- Shi-Bing Su4,
- Qing Jing5,
- Han-Fei Ding6,7, and
- Shuang Huang1,4,7,†
- 1Department of Biochemistry and Molecular Biology, Medical College of Georgia, Georgia Health Sciences University, Augusta, GA 30912, USA.
- 2State Key Laboratory of Genetic Engineering and MOE Key Laboratory of Contemporary Anthropology, Institute of Genetics, College of Life Science, Fudan University, Shanghai 200433, China.
- 3Department of Immunology and Medical Microbiology, University of Toledo Health Science Center, Toledo, OH 43606, USA.
- 4Research Center for Traditional Chinese Medicine Complexity System, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
- 5Changhai Hospital, Shanghai 200433, China.
- 6Department of Pathology, Medical College of Georgia, Georgia Health Sciences University, Augusta, GA 30912, USA.
- 7Cancer Center, Georgia Health Sciences University, Augusta, GA 30912, USA.
- ↵†Corresponding author. E-mail: shuang{at}gru.edu
-
↵* These authors contributed equally to this work.
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Science Signaling 12 Mar 2013:
Vol. 6, Issue 266, pp. ra16
DOI: 10.1126/scisignal.2003706
Vol. 6, Issue 266, pp. ra16
DOI: 10.1126/scisignal.2003706
Sungguan Hong
1Department of Biochemistry and Molecular Biology, Medical College of Georgia, Georgia Health Sciences University, Augusta, GA 30912, USA.
Hyangsoon Noh
1Department of Biochemistry and Molecular Biology, Medical College of Georgia, Georgia Health Sciences University, Augusta, GA 30912, USA.
Haoming Chen
2State Key Laboratory of Genetic Engineering and MOE Key Laboratory of Contemporary Anthropology, Institute of Genetics, College of Life Science, Fudan University, Shanghai 200433, China.
Ravi Padia
1Department of Biochemistry and Molecular Biology, Medical College of Georgia, Georgia Health Sciences University, Augusta, GA 30912, USA.
Zhixing K. Pan
3Department of Immunology and Medical Microbiology, University of Toledo Health Science Center, Toledo, OH 43606, USA.
Shi-Bing Su
4Research Center for Traditional Chinese Medicine Complexity System, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
Qing Jing
5Changhai Hospital, Shanghai 200433, China.
Han-Fei Ding
6Department of Pathology, Medical College of Georgia, Georgia Health Sciences University, Augusta, GA 30912, USA.
7Cancer Center, Georgia Health Sciences University, Augusta, GA 30912, USA.
Shuang Huang
1Department of Biochemistry and Molecular Biology, Medical College of Georgia, Georgia Health Sciences University, Augusta, GA 30912, USA.
4Research Center for Traditional Chinese Medicine Complexity System, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
7Cancer Center, Georgia Health Sciences University, Augusta, GA 30912, USA.
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