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Research ArticleCell Biology
An Adenosine-Mediated Signaling Pathway Suppresses Prenylation of the GTPase Rap1B and Promotes Cell Scattering
- Elizabeth Ntantie1,
- Patrick Gonyo1,*,
- Ellen L. Lorimer1,*,
- Andrew D. Hauser1,
- Nathan Schuld1,
- Donna McAllister2,
- Balaraman Kalyanaraman2,
- Michael B. Dwinell3,
- John A. Auchampach1, and
- Carol L. Williams1,†
- 1Department of Pharmacology and Toxicology, Cancer Center, and Cardiovascular Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
- 2Department of Biophysics and Cancer Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
- 3Department of Microbiology and Molecular Genetics and Cancer Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
- ↵†Corresponding author. E-mail: williams{at}mcw.edu
-
↵* These authors contributed equally to this work.
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Science Signaling 28 May 2013:
Vol. 6, Issue 277, pp. ra39
DOI: 10.1126/scisignal.2003374
Vol. 6, Issue 277, pp. ra39
DOI: 10.1126/scisignal.2003374
Elizabeth Ntantie
Department of Pharmacology and Toxicology, Cancer Center, and Cardiovascular Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Patrick Gonyo
Department of Pharmacology and Toxicology, Cancer Center, and Cardiovascular Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Ellen L. Lorimer
Department of Pharmacology and Toxicology, Cancer Center, and Cardiovascular Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Andrew D. Hauser
Department of Pharmacology and Toxicology, Cancer Center, and Cardiovascular Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Nathan Schuld
Department of Pharmacology and Toxicology, Cancer Center, and Cardiovascular Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Donna McAllister
Department of Biophysics and Cancer Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Balaraman Kalyanaraman
Department of Biophysics and Cancer Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Michael B. Dwinell
Department of Microbiology and Molecular Genetics and Cancer Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
John A. Auchampach
Department of Pharmacology and Toxicology, Cancer Center, and Cardiovascular Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Carol L. Williams
Department of Pharmacology and Toxicology, Cancer Center, and Cardiovascular Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
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