Research ArticleImmunology The Deubiquitinase A20 Mediates Feedback Inhibition of Interleukin-17 Receptor Signaling Abhishek V. Garg1, Mushtaq Ahmed1, Abbe N. Vallejo2, Averil Ma3, and Sarah L. Gaffen1,*1Division of Rheumatology and Clinical Immunology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA.2Department of Pediatrics, Children’s Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, PA 15224, USA.3Department of Medicine, University of California at San Francisco, San Francisco, CA 94143, USA.↵*Corresponding author. E-mail: sig65{at}pitt.edu See allHide authors and affiliations Science Signaling 04 Jun 2013:Vol. 6, Issue 278, pp. ra44DOI: 10.1126/scisignal.2003699 Abhishek V. Garg 1Division of Rheumatology and Clinical Immunology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site Mushtaq Ahmed 1Division of Rheumatology and Clinical Immunology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site Abbe N. Vallejo 2Department of Pediatrics, Children’s Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, PA 15224, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site Averil Ma 3Department of Medicine, University of California at San Francisco, San Francisco, CA 94143, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site Sarah L. Gaffen 1Division of Rheumatology and Clinical Immunology, Department of Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA.Find this author on Google Scholar Find this author on PubMed Search for this author on this site For correspondence: sig65@pitt.edu Article Figures & Data Info & Metrics eLetters PDF Article Information vol. 6 no. 278 ra44 DOI: https://doi.org/10.1126/scisignal.2003699 PubMed: 23737552 Published By: Science Signaling Print ISSN: 1945-0877 Online ISSN: 1937-9145 History: Received October 15, 2012Accepted May 16, 2013 . Copyright & Usage: Copyright © 2013, American Association for the Advancement of Science Author Information Altmetric Article usage Article lifetimeLast 6 monthsThis monthArticle usage: June 2013 to April 2021 AbstractFullPdf Jun 20131750184317 Jul 20133014377 Aug 20131874264 Sep 20131362245 Oct 20131501938 Nov 20131331729 Dec 2013153631 Jan 20141422032 Feb 20141111834 Mar 2014733242 Apr 2014592222 May 2014621219 Jun 2014641112 Jul 201456913 Aug 20144877 Sep 2014411511 Oct 2014481110 Nov 2014341718 Dec 201415167 Jan 2015262313 Feb 201533139 Mar 2015331724 Apr 2015371711 May 20151487 Jun 201528510 Jul 201522410 Aug 2015459 Sep 201538519 Oct 201520513 Nov 20155713 Dec 20151829 Jan 201665315 Feb 20163315 Mar 20165046 Apr 20162706 May 20162833 Jun 20165334 Jul 20163347 Aug 20164328 Sep 20163746 Oct 20165034 Nov 2016104210 Dec 20166955 Jan 20175259 Feb 20174887 Mar 20175424 Apr 20174343 May 20174134 Jun 20174756 Jul 20175424 Aug 20176443 Sep 20174038 Oct 20173953 Nov 20174825 Dec 20172215 Jan 20183934 Feb 20185064 Mar 20183581 Apr 20186163 May 20188084 Jun 201858108 Jul 20184495 Aug 2018212210 Sep 2018261811 Oct 201838136 Nov 2018351610 Dec 201834136 Jan 201931149 Feb 20194895 Mar 20192995 Apr 20191152 May 20191585 Jun 201915143 Jul 201924129 Aug 201910117 Sep 20191043 Oct 2019271011 Nov 20192252 Dec 2019291010 Jan 202022203 Feb 2020520 Mar 202041127 Apr 20203041 May 202032127 Jun 20206595 Jul 20201271 Aug 20201461 Sep 20202599 Oct 202030113 Nov 20202364 Dec 202020109 Jan 20212488 Feb 20211646 Mar 20213084 Apr 2021731 View Full Text
The Deubiquitinase A20 Mediates Feedback Inhibition of Interleukin-17 Receptor Signaling By Abhishek V. Garg, Mushtaq Ahmed, Abbe N. Vallejo, Averil Ma, Sarah L. Gaffen Science Signaling04 Jun 2013 : ra44 Inhibition of an inflammatory cytokine signaling pathway by A20 at the receptor may play a role in preventing autoimmunity. Supplementary Materials
The Deubiquitinase A20 Mediates Feedback Inhibition of Interleukin-17 Receptor Signaling By Abhishek V. Garg, Mushtaq Ahmed, Abbe N. Vallejo, Averil Ma, Sarah L. Gaffen Science Signaling04 Jun 2013 : ra44 Inhibition of an inflammatory cytokine signaling pathway by A20 at the receptor may play a role in preventing autoimmunity. Supplementary Materials